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mRNAs and the subsequent translation into proteins and then also through posttranslational modi cation of the proteins. Compartmentalization within the cell is critical location matters. Subsets of proteins can be examined based on secretion, membrane location, phosphorylation, glycosylation, antigenic properties, and other categories (Hanash and Beretta, 2002). For decades proteins have been displayed as spots on twodimensional gels, separating proteins by charge and by size. Actually, this approach was rather discouraging, because so few of the many spots visualized could be identi ed. Genome sequences and mass spectrometry of proteins have dramatically altered this situation. New methods are appearing rapidly; three journals dedicated to proteomics have been launched in the past year (Proteomics, Brie ngs in Functional Genomics and Proteomics, Journal of Proteomics Research; joining Molecular & Cellular Proteomics). Organizationally, there is now an international Human Proteome Organization (HUPO), patterned after the quite successful Human Genome Organization (HUGO) (Abbott, 2001). Measuring both protein and gene expression is important, because evidence is accumulating that the two levels are often not closely correlated. Many other factors besides transcription of the gene are important. These factors include splicing, translation, posttranslational modi cations, binding, catabolism, and clearance. Some protein biomarkers will be related to drug action.

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Pro les have settings associated with them, and these settings can be used to change the data in the pro le Creating multiple pro les for a single Web site, each with its own settings, results in multiple pro les with very different data Why is this important You can change how the data looks and who has access to the data using various Pro le Settings, as we explain in 5 When you fully leverage the account and pro le structure, you can create multiple sets of data for multiple Web sites or for the same Web site, and you can grant access to multiple users (see the example in Figure 47) At the top level is, for example, Bob s Google Analytics Account This account has access to two Google Analytics Accounts: Bob s personal Analytics Account and his work Analytics Account.

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At the applications layer, the entire design of the XG mobile network is driven by the need for openness and programmability in order to facilitate the rapid deployment of innovative new services Clearly, allowing third parties, many of whom may not be telecommunications or even networking experts, to develop applications also raises the possibility of inadvertent as well as malicious security faults Further, the more complex and sophisticated applications become, the more likely that they will become vulnerable to security breaches Finally, we believe that aside from protecting the network itself, security will become a key differentiator in the eyes of end users as well as third-party service and content providers In fact, it is possible that security itself, in the form of trust brokerage or credentials services, may become a revenue-generating service in its own right.

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In this part, we describe three key topics of security research that are applicable to threats at various layers in the XG mobile network, namely, cryptography, AAA, and secure code We begin with 10, which discusses the fundamental issues in cryptography as they apply to network systems 10 rst covers some cryptographic techniques that are currently used in 2G and 3G systems This includes secret-key cryptography, as used in GSM and 3GPP systems, public-key cryptography, as used in SSL, and proposal for a general publickey infrastructure (PKI) The chapter then de nes the formal notion of a secure cryptosystem, in terms of provable security, using public-key encryption and signing as examples.

The last part of the chapter summarizes important research directions in applying cryptography for securing XG mobile systems, including cryptographic techniques for coping with heterogeneity, the development of ef cient cryptographic primitives required in the resource-constrained mobile wireless environment, and the development of trusted or tamper-resistant devices 11 addresses a key practical issue in network security, namely, Authentication, Authorization, and Accounting (AAA) After de ning the terms and the evolution of AAA and the special needs of AAA in mobile networks, the chapter introduces a common framework for discussing AAA research It then describes current AAA technologies, particularly protocols such as RADIUS, Diameter, PANA, EAP, WLAN protocols, and 3GPP as well as 3GPP2 approaches.

, and M D Smith (2002) Mathematical Statistics with Mathematica New York: Springer Verlag Ross, S (1976)The arbitrage theory of capital asset pricing J Econ Theory 13: 341 360 Rubinstein, M (1973) A mean-variance synthesis of corporate nance theory J Fin (March) 28: 167 182 Rubinstein, M (1976) The valuation of uncertain income streams and the pricing of options Bell J Econ Manag Sci 7: 407 425 Salvatore, D (1999) Lessons from the nancial crisis in East Asia J Pol Modeling 21: 283 347 Salvatore, D, and D Reagle (2000) Forecasting nancial crises in emerging market economies Open Econ Rev 11: 247 259 Samuelson, P (1983) Foundations of Economic Analysis Cambridge: Harvard University Press Santangelo, G (2004) Analysis of international data revision: Theory and application PhD dissertation Economics Department, Fordham University Schaller, H, and S van Norden (1997) Regime switching in stock market returns Appl Fin.

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