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Extending general Grid attributes to communication services and network resources has been an evolutionary process A key goal has been to ensure that these services and resources can be closely integrated with multiple other co-existent Grid services and resources This close integration is one of the capabilities that enable networks to become full participants within Grid environments, as opposed to being used as generic, accessible external resources Almost all Grids are implemented as distributed infrastructure Therefore, from the earliest days of their design and development, Grids have always utilized communications services, especially those based on TCP/IP (transmission control protocol/Internet protocol) Grids could not have been developed without the Internet, a widely deployed, inexpensive data communications network, based on packet routing As discussed elsewhere in this book, the Internet and Grids share a number of basic architectural concepts.

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Many fundamental Grid concepts incorporated new approaches to networking created for specialized projects, such as the innovative I-WAY project (Information Wide Area Year), which was based on an experimental broadband network implemented for Supercomputing 95 [9] The I-WAY project demonstrated for the first time that a national network fabric could be integrated to support large-scale distributed computing The software created for that project became the basis for the most widely implemented Grid software used today [10] However, until recently, the mechanisms that allow networks to be fully integrated into Grid environments did not exist, in part because Grid architectural concepts differ from those that have governed the design of traditional networks Before the Internet, traditional networks were designed specifically to support a narrow range of precisely defined communication services These services were implemented on fairly rigid infrastructure, with minimal capabilities for ad hoc reconfiguration.

Creating awareness among IT management draw attention to the importance of architecture. Involving business attention for thinking in terms of development strategies and target-oriented nature of architecture. Introducing cohesion into architectural initiatives with the aid of the architectural framework. Introducing business case teams.

k and Ej/mV AN 84.8 77.7 103.7 TMS 3.94 5.32 6.69 8.8 17.6 15.2 30.6 3.5 7.5 16.9 16.9 DMF 35.4 37.4 52.4 1.6 3.2 11.4 22.9 4.8 0.3 2.9 13.3 DMSO 17.5 16.8 24.1 1.2 2.4 9.4 18.7 4.9 2.4 2.6 11.2 NMA 11.5 11.9 16.9 1.1 2.3 11.2 22.5 4.9 0.2 1.9 13.1 MeOH 60.5 47.0 70.8 7.4 14.8 4.6 9.3 5.1 8.3 14.4 6.2

1.13 1.69 3.10 2.05 2.21 2.50 1.99

Such traditional networks were designed with the assumptions that target service requirements are known, and that the supporting infrastructure would remain relatively unchanged for many years Traditional networks were provisioned so that they could be used as resources external to other processes, with minimal capabilities for dynamic configurations or ad hoc resource requests They have been centrally managed and controlled resources The Internet design has been a major benefit to Grid deployments Unlike legacy telecommunications infrastructure, which has had a complex core and minimal functionality at the edge, the Internet places a premium on functionality at the edge supported by a fairly simple core This end-to-end design principle, described in 10, enables innovation services to be created and implemented at the edge of the network, provides for high-performance network backbones, and allows for significant service scalability.

1.1 1.2 1.3 1.4 Wha t Is a Dis tr ibute d Sys te m Examples of Distributed Systems Distributed System Requirements Transparency in Distributed Systems

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Because the Internet generally has been provisioned as an overlay on legacy communications infrastructure, its potential to support Grid communications services.

Ovarian Tumors of Low Malignant Potential (oophorectomy). Both Zanetta and associates16 and Rao and colleagues15 had similar recurrence rates 19% and 16% versus 5% and 4%, respectively, for patients undergoing fertility-sparing surgeries compared to surgical treatment that included hysterectomy with removal of both adnexae. The risk of recurrence increases when fertility-sparing surgeries are performed on bilateral or multifocal lesions.17 If recurrence does occur, surgical resection alone is usually curative. Favorable features that are associated with decreased risk of recurrence are small, grossly unilateral lesions, and intact removal of the cyst.

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