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Thanks to everadvancing science, we already have drugs that bulk up our muscles and whisk away our wrinkles; soon we may be able to pop a pill to help us ace our SATs, or forget bad memories, or change our personalities dramatically Someday, too, we will undoubtedly be able to clone human embryos, harvest their near-miraculous stem cells, and use those cells to develop medical treatments; scientists in South Korea have already gotten as far as the harvesting But should we Although the FDA may argue that its role is merely to decide whether the drugs work safely, politicians and religious leaders will turn any yes or no into a socio-political statement The FDA is facing pressure to do more than file away the data it gets when drugs are tested Angry physicians, patients, and politicians want it to make more of the results public.

D (1834)

Splitting Value: 4955

The agency itself would like to see further trials done after drugs are on the market, because the pre-approval trials cannot catch those 1-in-1,000 adverse reactions However, the reg-.

Open Systems Interconnection OSS Operations Support Systems OSS/J OSS Through Java Initiative OTA Over-the-Air (con guration) OWL Web Ontology Language PAOS Reverse HTTP binding for SOAP PBM Policy-Based Management PCF Point Coordination Function (802.11) or Policy Control Function (3GPP) P-CSCF Proxy CSCF PCMCIA Personal Computer Memory Card International Association PDA Personal Digital Assistant PDF Policy Decision Function PDP Packet Data Protocol PKI Public Key Infrastructure PLMN Public Land Mobile Network POP3 Post Of ce Protocol 3 POST HTTP request method PPP Point-to-Point Protocol PSTN Public Switched Telephone Network PTT Push-To-Talk

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11 We are not aware of all these processes during most of our interactions. Is this because people are so predictable, or because we are not aware of the complexity of understanding

Let s take a look at how this AntiPattern often comes into being. Imagine that you are building an application to synchronize two of your company s databases. You have created timer-based beans for pooling the databases for changes, and two matching message beans for handling updates. This gives you a design like the one pictured in Figure 8.5. Since you have one sender and one receiver for each message, and the messages must be persistent to ensure that none are lost, you use queues.

FIgUre 28-7 How you specify the value for an editable attribute in the Template Properties dialog box depends on the type of attribute.

2. Choose Modify Templates Make Attribute Editable to display the Editable Tag Attributes dialog box as shown in Figure 28-6.

operators or service providers);

useless (not just in magnitude, but also when it came to the arithmetic signs), precisely at the most stressful time when shelter was most unavoidably urgently needed. Huge mark-to-market losses were in icted. There were reports of wounded hedge funds considering abandoning altogether the now demonstrably hazardous, complex credit space. Many punters apparently grew angry at the models. What triggered the massacre What helped bring mathematical sacredness down to earth What helped expose the unreliability and perilousness of the models The downgrade, on May 5, by Standard & Poor s of carmakers General Motors and Ford to junk debt status, which inspired a sharp rise in idiosyncratic risk and a widening of credit index spreads. While those spreads eventually returned to precrisis levels, the effects on the correlation market (the market for tranches) proved more structural, with relative tranche valuations adapting to the new reality much more resiliently. Why did Ford and GM have such a large impact For starters, they are pretty big borrowers and many credit structures contained their names as references. They had also been in trouble for a while, keeping the market nervous and on a constant state of alert. On May 4, such sleep-depriving concerns appeared welcomingly assuaged after uber-investor Kirk Kerkorian announced a large investment in GM. Hope reigned supreme among pros. So when S&P dropped the junk bomb the very next day, the short-lived dream was shattered so violently that the whole thing unraveled badly. And it did so in unexpected ways, affecting the values of different CDO tranches in such fashion as to render the mathematical guidance dangerously unhelpful.

Expanded Tables mode is best used on an as-needed basis, and you can quickly toggle between it and Standard mode by pressing F6 (Option+F6).

Rule 3 IF Class of work is State-gov and Education is 9th THEN Income is 50K (Count: 6; Support: 0.00018; Con dence: 1; Lift: 1.32) Rule 4 IF Class of work is Self-emp-inc and Education is Prof-school THEN Income is >50 K (Count: 78; Support: 0.0024 Con dence: 0.96; Lift: 4) Rule 5 IF Class of work is Local-gov and Education is 12th THEN Income is 50 K (Count: 17; Support: 0.00052; Con dence: 0.89; Lift: 1.18)

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