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4.3.1.4 False Discovery Rate (FDR) Control Statistical procedures for the identi cation of differentially expressed genes can be treated as multiple hypothesis testing. A p-value threshold that is appropriate for a single test does not provide good control on false positive discovery for the overall procedure. For example, testing of 10,000 genes with p-value threshold of 0.05 is expected to identify 10, 000 0.05 = 500 genes as differentially expressed even if none of the genes are actually differentially expressed. The false positive rate can be controlled by evaluating the expected proportion of true rejected null hypotheses out of the total number of rejected null hypothesis. An example of FDR control is shown in Figure 4.11. If N is the total number of genes, 0 is the p-value threshold, and pi (i = 1, . . . , N) are p-values in ascending order, then the ith ranked gene is selected if pi 0 i/N [32]. A comprehensive review of this statistical FDR control is presented in the work by Qian and Huang [33]. It is worth noting that a bootstrap procedure for FDR control has also been introduced [29] and was shown to be suitable for gene selecting when data distribution deviates from normal distribution.

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The controlled mobility of the sensor nodes (rather than the mobility of an autonomous router or of the sink) is explored in [154] The idea here is to have the sensors move into positions that minimize the energy cost of reporting streams of data to the sink The problem of reducing energy consumption and of maximizing the lifetime of a sensor network by exploiting controllable sink mobility within the network has been tackled in [155] and, more recently, in [156] In these two works, it is the sink that moves directly among the (static) sensor nodes and, while sojourning at given locations, collects data that are sent to it via multi-hop (ad hoc) routing The rst paper is mostly concerned with energy minimization The authors present an ILP (Integer Linear Programming) model to determine the locations of multiple sinks and the routes from the sensors to the sinks.

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Listing 14-5 shows the code for the home interface. All you need is a create method as required by the EJB specification for session beans. Remember that you cannot pass arguments to the create method for stateless session beans. Listing 14-5: Code for the home interface package chapter14.stocktrader; import java.rmi.RemoteException; import javax.ejb.CreateException; import javax.ejb.EJBHome; public interface StockTraderHome extends EJBHome { StockTrader create() throws CreateException, RemoteException; }

(a) Psychologists include in written and oral reports and consultations, only information germane to the purpose for which the communication is made. (b) Psychologists discuss confidential information obtained in their work only for appropriate scientific or professional purposes and only with persons clearly concerned with such matters.

Time is divided into rounds At the beginning of each round, information on the nodes residual energy is centrally gathered and the ILP problem is solved to determine new, feasible locations the sinks should travel in order to minimize the maximum energy consumption spent at the nodes during that round Minimizing the energy consumption results in increased network longevity No constraints are forced on the sink movements and successive.

6.4 6.4.1

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One of the main developments in call-centre design, indeed, of any installation requiring that telephony and computing be integrated, has been a move over to standardised interfaces [110] Until a few years ago, PABXs and ACDs, even if they did have computing interfaces, all used their own proprietary speci cation This has been gradually eroded by the work of the computer manufacturers and, in particular, one of their standardisation bodies, European Computer Manufacturers Association (ECMA), which realised that promoting an open standard would be bene cial to their industry (and incidentally perhaps adversely affecting that of the PBX manufacturers) They took on board the Telephone Server Application Interface (TSAPI) originally developed by Novell and AT&T, and portable across a number of operating systems.

public public public public public public public public class networkBrokerInterface{ static nal byte SOCKET_UDP 17; static nal byte SOCKET_TCP 6; networkBrokerInterface(); int socket(byte type); int setSocketTimeout(int sd, int timeout); int connect(int sd, InetAddress dest, short port); int bind(int sd, short port);

i =

Of course in the computer world, not everyone agrees to this single standard : Microsoft offer an alternative in the form of TAPI, which is centred on a PC architecture rather than TSAPI s server bias and integrates Microsoft s ActiveX components The original positioning of the two alternatives was clear: TAPI was intended for the smaller end of the call-centre market, with TSAPI covering the larger, but the differences have been reduced with time There is now also a Java-based JTAPI environment available As the simple, basic call-centre requirement extends to encompass more of back-end processing such as scheduled follow-ups to telephone calls in the form of fax, eMail or even physical mail envelop-stuf ng, the range of customised design will increase and more exible tools will be required.

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Read or load a PDF file and extract its text content in C# and VB. NET application with GemBox.Document library.

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