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The single-celled green alga, Chlamydomonas reinhardi, has been used in the study of extrachromosomal inheritance for several reasons. First, it has a single, large chloroplast; it can survive by culture technique even when the chloroplast is not functioning; and nally, it shows some interesting non-Mendelian inheritance patterns related to mating type. R. Sager has done extensive work on the inheritance of streptomycin resistance in Chlamydomonas. Streptomycin resistance can be selected for in Chlamydomonas in several ways. Normal cells, sensitive to the antibiotic, are killed in its presence. If cells are grown in low levels of the antibiotic (100 g/ml), some cells show resistance to it. When these cells are crossed

142 Derive the detailed truth table and draw a timing diagram for the JK ip- op, using the two ip- op model of Figure 147 143 The speed of the rotating encoder of Focus on Measurements: Digital Measurement of Angular Position and Velocity is found to be 9,425 rad/s The encoder timer reads 10 and the clock counter reads 300 Assuming that both the timer counter and the encoder counter started at zero, nd the clock frequency

Ruth Sager (1918 1997).

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The design of sequential circuits, just like the design of combinational circuits, can be carried out by means of a systematic procedure You will recall how the Karnaugh map, introduced in 13, allowed us to formalize the design procedures for an arbitrary combinational circuit The equivalent of a Karnaugh map for a sequential circuit is the state diagram, with its associated state transition table To illustrate these concepts, it is best to proceed with an example Consider the three-bit binary counter of Figure 1426, which is made up of three T ip- ops You can easily verify that the input equations for this counter are T1 = 1, T2 = q1 , and T3 = q1 q2 Knowing the inputs, we can determine the three outputs from these relationships at any time The outputs Q1 , Q2 , and Q3 form the state of the machine It is straightforward to show that as the clock goes through a series of cycles, the counter will go through the transitions shown in Table 141, where we indicate the current state by lowercase q and the next state by an uppercase Q Note that the state diagram of Figure 1426 provides information regarding the sequence of states assumed by the counter in graphical form In a state diagram, each state is denoted by a circle called a node, and the transition from one state to another is indicated by a directed edge, that is, a line with a directional arrow The analysis of sequential circuits consists of determining either their transition table or their state diagram The reverse of this analysis process is the design process How can one systematically arrive at the design of a sequential circuit, such as a counter, by

Table 141 State transition table for three-bit binary counter Current state q3 0 0 0 0 1 1 1 1 q2 0 0 1 1 0 0 1 1 q1 0 1 0 1 0 1 0 1 T3 0 0 0 1 0 0 0 1 Input T2 0 1 0 1 0 1 0 1 T1 1 1 1 1 1 1 1 1 Q3 0 0 0 1 1 1 1 0 Next state Q2 0 1 1 0 0 1 1 0 Q1 1 0 1 0 1 0 1 0

(Courtesy of Dr. Ruth Sager.)

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